Get Molecular, Genetic, and Nutritional Aspects of Major and PDF

By James F Collins

ISBN-10: 0128021683

ISBN-13: 9780128021682

ISBN-10: 0128023767

ISBN-13: 9780128023761

Molecular, Genetic, and dietary elements of significant and hint Minerals is a distinct reference that gives a whole review of the non-vitamin micronutrients, together with calcium, copper, iodine, iron, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, sodium, and zinc.

In addition, the booklet covers the dietary and toxicological homes of nonessential minerals chromium, fluoride and boron, and silicon and vanadium, in addition to ultra-trace minerals and people without confirmed nutritional requirement for people. clients will locate in-depth chapters on each one crucial mineral and mineral metabolism, besides discussions of nutritional techniques within the usa and round the world.

  • Presents the single clinical connection with disguise the entire nutritionally proper crucial significant and hint minerals
  • Provides a large introductory bankruptcy on every one mineral to provide readers helpful history and context
  • Clarifies the mobile and molecular points of every mineral and its genetic and genomic aspects
  • Includes assurance of all nutritionally correct minerals―essential significant hint minerals and ultra-trace minerals
  • Underscores the real interactions among minerals so readers find out how metabolism of 1 mineral impacts another

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Additional resources for Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals

Example text

Overall, the burden associated with obesity and related NCDs is important, especially considering that it is a preventable condition. , 2015). , 2014). It is currently accepted that it is not the amount of adipose tissue, but the quality of the tissue that leads to healthy or unhealthy phenotypes (Bays, 2011), in which dysfunctional or “sick” adipose tissue mediates the development of obesity-related diseases (Fig. 1). The location of adipose tissue depots is also an important determinant of adipose tissue-related pathogenesis (Karpe and Pinnick, 2015).

In addition, transgenic expression of VDR only in the intestine of VDR null mice also results in normalization of serum calcium and bone mineralization (Xue and Fleet, 2009). These findings suggest that a major effect of 1,25(OH)2D3/VDR is to provide calcium to bone by stimulating intestinal absorption. In summary, data from in vivo and in vitro studies suggest that the effects of 1,25(OH)2D3 on bone are diverse and that 1,25(OH)2D3 can affect bone formation and resorption. GENOMIC MECHANISM OF 1,25-DIHYDROXYVITAMIN D3 ACTION The molecular mechanism of 1,25(OH)2D3 action is similar to that of other steroid hormones.

Calcium-Directed Adipocyte Pathogenesis Being a highly dynamic intracellular messenger, Ca2+ regulates several processes within cells, including cell homeostasis, proliferation, differentiation, death, and communication with other cells and the environment. These processes directly determine adipose tissue physiology, thus greatly impacting the development of obesity and its comorbidities. After briefly reviewing basic concepts of calcium regulation at the intracellular level (Fig. 3), the role of calcium in several aspects of adipocyte function and pathogenesis will be discussed.

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Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals by James F Collins

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