James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander's Molecular Biology of the Gene (7th Edition) PDF

By James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick

ISBN-10: 0321762436

ISBN-13: 9780321762436

Now thoroughly up to date with the most recent learn advances, the Seventh variation of James D. Watson’s vintage ebook, Molecular Biology of the Gene retains the distinct personality of previous variants that has made it the main popular e-book in molecular biology. Twenty-two concise chapters, co-authored by means of six hugely extraordinary biologists, offer present, authoritative insurance of a thrilling, fast-changing discipline. 

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Extra resources for Molecular Biology of the Gene (7th Edition)

Example text

In a cross between RR and rr, fertilization produces an Fl plant with both alleles (Rr). The seeds look round because R is dominant over r. We refer to the appearance or physical structure of an individual as its phenotype, and to its genetic composition as its genotype. Individuals with identical phenotypes may possess different genotypes; thus, to determine the genotype of an organism, it is frequently necessary to perform genetic crosses for several generations. , RR or rr). , Rr) are called heterozygous.

To obtain a more accurate approximation of the distance between the outside markers, we calculate the probability (ac  cb) that when a crossover occurs between c and b, a crossover also occurs between a and c, and vice versa (cb  ac). This probability subtracted from the sum of the frequencies expresses more accurately the amount of recombination. The simple formula ab ¼ ac þ cb À 2(ac)(cb) A C B a c b × 1-7 The use of three-factor crosses to assign gene order. The least frequent pair of reciprocal recombinants must arise from a double crossover.

1982. The growth of biological thought: Diversity, evolution, and inheritance. Harvard University Press, Cambridge, Massachusetts. A. 1966. The gene: A critical history. Saunders, Philadelphia. McClintock B. 1951. Chromosome organization and gene expression. Cold Spring Harbor Symp. Quant. Biol. 16: 13– 57. ———. 1981. Genes, radiation, and society: The life and work of HJ. Muller. Cornell University Press, Ithaca, New York. ———. 1984. The significance of responses of genome to challenge. Science 226: 792 –800.

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Molecular Biology of the Gene (7th Edition) by James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick

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