By W.-D. Heiss (auth.), Professor Dr. med. Wolf-Dieter Heiss (eds.)
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Extra resources for Functional Mapping of the Brain in Vascular Disorders
More advanced techniques of chemical shift imaging can produce strict image of each energy metabolite (Per, Pi, ATP). Accordingly, we performed experiments on a high-speed method of spatially resolved high-resolution NMR spectroscopy for biological systems and obtained the results set out below . 5 Tesla operating our IH-NMR imager. Spin echo trains induced by periodical inversions of the field gradient were further phase-modulated by pulse applications of other field gradients. Aims on Phosphorus-31 Magnetic Resonance Imaging 27 Such phase-modulated echo trains can be converted to three- or fourdimensional data, including both spectroscopic and spatial information, by means of suitable data manipulation involving echo rearrangement and multidimensional Fourier transformation.
Proc Nat! Acad Sci USA 75:4925-4929 28 K. : Aims on Phosphorus-31 Magnetic Resonance Imaging 7. Doyle FH, Gore IC, Pennock 1M, Bydder GM, Orr IS, Steiner RE, Young IR, Burl M, Clow H, Gilderdale DI, Bailes DR, Walters PE (1981) Imaging of the brain by nuclear magnetic resonance. Lancet 11:8237-8241 8. Edelstein WA, HutchisonIMS, SmithFW, Mallard I, Iohnson G, Redpath TW (1981) Human whole-body NMR tomographic imaging: normal sections. Br I Radiol54: 149151 9. Edwards RHT, Dawson MI, Wilkie DR, Gordon RE, Shaw D (1982) Clinical use of nuclear magnetic resonance in the investigation of myopathy.
While the fractional extraction of oxygen remains normal, the ratio of regional cerebral blood volume to blood flow is seen to increase [12,28], but this has been reported to revert to normal following vascular surgery [13, 29]. Sickle cell anemia patients, another clinical category of patients in whom cerebral infarction tends to occur, have be~n studied with PET. They have an incidence of major strokes at a young age. A PET study of young adults has shown that regional cerebral oxygen utilization is mismatched to blood flow.
Functional Mapping of the Brain in Vascular Disorders by W.-D. Heiss (auth.), Professor Dr. med. Wolf-Dieter Heiss (eds.)