Download e-book for iPad: Diastolic Relaxation of the Heart: The Biology of Diastole by Ketty Schwartz, Kenneth R. Boheler (auth.), Beverly H.

By Ketty Schwartz, Kenneth R. Boheler (auth.), Beverly H. Lorell M.D., William Grossman M.D. (eds.)

ISBN-10: 1461361109

ISBN-13: 9781461361107

ISBN-10: 1461525942

ISBN-13: 9781461525943

Numerous stories have documented the significance of diastolic disorder in middle sickness. Now, delivering cardiologists with the most up-tp-date details to be had at the topic, the editors have pulled jointly contributions from a magnificent array of most sensible researchers and compiled them into one entire, conscientiously edited resource, Diastolic rest of the guts, moment variation: TheBiology of Diastole in health and wellbeing and Disease.
This fresh moment variation, in keeping with a up to date assembly, contains such issues as:

  • molecular biology of leisure;
  • consequences of altered gene expression;
  • impaired leisure in experimental types (ischemia and hypoxia, and hypertrophy and failure);
  • diastolic disorder within the diseased human middle.

Diastolic leisure of the center, moment version: The Biology ofDiastole in health and wellbeing and Disease, the successor to the editors' bestselling paintings at the related topic, released in 1987 - belongs at the shelf of each training heart specialist. it's going to even be a useful addition to the library of scientists learning the results of diastole on middle functionality.

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Extra info for Diastolic Relaxation of the Heart: The Biology of Diastole in Health and Disease

Example text

Alil ]E, et al. (1989). Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle. Circ Res 64: 1041. 19. Ieki K, et al. (1989). Effect of long-term treatment with ~-blocker on cardiac hypertrophy in SHR. ] Moll Cell Cardiol 21(Suppl V):ll3. 20. Medugorac I, et al. (1983). Characterization of left ventricular collagen in the rat. Cardiovasc Rex 17: 15 . 21. Ignotz RA, et al. (1988). ] Bioi Chern 261:4337. 22. Sporn MB, et al. (1987). Some recent advances in the chemistry and biology of transforming growth factor-beta.

As assessed by adrenergic receptor and antagonist studies, the increase in ANF release and upregulation of ANF gene expression are primarily ulA-mediated responses {l2}. Through transfection and transient assays of a series of ANF luciferase and MLC-2 luciferase fusion genes in neonatal rat myocardial cells, we have recently demonstrated that 638 bp fragment of ANF promoter contains sufficient information to confer inducible expression to a luciferase reporter gene. Within this fragment we have recently identified two discrete cis elements (AF-l and AF-2) that may be important in mediating inducible expression {l3}.

J BioI Chem 262:1740-1747. Inui M, Saito A, Fleischer S (1987). Isolation of the ryanodine receptor from cardiac sarcoplasmic reticulum and identify with the feet structures. J BioI Chem 262:15637-15642. Wagenknecht T, Grassucci R, Frank J, Saito A, Inui M, Fleischer S (1989). Three dimensional architecture of the calcium channel/foot structure of sarcoplasmic reticulum. Nature 338:167-170. lai FA, Erickson HP, Rousseau E, liu Q-Y, Meissner G (1988). Purification and reconstitution of the 3. SARCOPLASMIC RETICULUM GENE EXPRESSION IN HUMAN HEART FAILURE 6.

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Diastolic Relaxation of the Heart: The Biology of Diastole in Health and Disease by Ketty Schwartz, Kenneth R. Boheler (auth.), Beverly H. Lorell M.D., William Grossman M.D. (eds.)


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