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By Traizet M.

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Internal pulse generators from both manufacturers are classified into three main categories – single channel, dual channel, and rechargeable devices. Single Channel Internal Pulse Generator These devices provide stimulation to one single deep brain stimulation lead. Hence, a single channel internal pulse generator has less volume of hardware and requires a smaller sized battery. Given its compact size, it is most suitable for patients with a lean body mass. 36 Aasef G. Shaikh and Hubert H. Fernandez The other advantage of a single channel pulse generator is that, because one internal pulse generator is responsible for modulating one lead, in cases of malfunction of one internal pulse generator during bilateral deep brain stimulation, the second side would remain functional.

The number and location of axons that are stimulated can be adjusted by changes in the voltage. Higher voltages can stimulate more axons by increasing the spatial extent of the electrical field intensities. Within the electrical field, increasing the voltage can increase the number of axons stimulated. The type of axon that is stimulated can be manipulated by changes in the pulse width. 40 Aasef G. Shaikh and Hubert H. Fernandez The electrode is here placed in the Vim for illustration. C+: the neurostimulator is used as the anode.

In: Deep Brain Stimulation Editor: Raja Mehanna ISBN: 978-1-63483-282-3 © 2015 Nova Science Publishers, Inc. Chapter 2 BASAL GANGLIA PHYSIOLOGY AND DBS FOR PARKINSON’S DISEASE: INTRODUCTION AND POSTULATED MECHANISMS Pornpimol Anprasertporn MD, Neda Hidarilak MD and Harrison Walker MD University of Alabama at Birmingham, Birmingham, AL, US ABSTRACT After reviewing the historical development of deep brain stimulation (DBS) as a therapy in the first chapter, and before we dive into its clinical applications in different disorders, we will here review the motor circuitry of the basal ganglia, how it is dysfunctional in Parkinson’s disease, then the postulated mechanism of action of DBS.

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A balancing condition for weak limits of families of minimal surfaces by Traizet M.


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